Laboratory of Lymphocyte Signaling and Oncoproteome

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Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia (T-PLL)

Staber, Philipp B.Herling, MarcoBellido, MarJacobsen, Eric D.Davids, Matthew S.Kadia, Tapan MahendraShustov, AndreiTournilhac, OlivierBachy, EmmanuelZaja, FrancescoPorkka, KimmoHoermann, GregorSimonitsch, IngridHaferlach, ClaudiaKubicek, StefanMayerhoefer, MariusHopfinger, GeorgJaeger, UlrichDearden, ClaireBlood, 2019

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Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL

Schrader, A Crispatzu, G Oberbeck, S Mayer, P Pützer, S von Jan, J Vasyutina, E Warner, K Weit, N Pflug, N Braun, T Andersson, EI Yadav, B Riabinska, A Maurer, B Ventura Ferreira, MS Beier, F Altmüller, J Lanasa, M Herling, CD Haferlach, T Stilgenbauer, S Hopfinger, G Peifer, M Brümmendorf, TH Nürnberg, P Elenitoba-Johnson, KSJ Zha, S Hallek, M Moriggl, R Reinhardt, HC Stern, MH Mustjoki, S Newrzela, S Frommolt, P Herling, MNature Communications, 2018

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Targeting transcription-coupled nucleotide excision repair overcomes resistance in chronic lymphocytic leukemia

Lohmann, G Vasyutina, E Bloehdorn, J Reinart, N Schneider, J Babu, V Knittel, G Crispatzu, G Mayer, P Prinz, C‎ Biersack, B Efremov, D Chessa, L Herling, CD Stilgenbauer, S Hallek, M Schobert, R Reinhardt, HC Schumacher, B‎ Herling, MLeukemia, 2017

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Re-activation of mitochondrial apoptosis inhibits T cell lymphoma survival and treatment resistance

Spinner, S Crispatzu, G Yi JH Munkhbaatar, E Mayer, P Höckendorf, U Müller, N Li, Z Schader, T Bendz, H Hartmann, S Yabal, M Pechloff, K Heikenwalder, M Kelly, GL Strasser, A Peschel, C Hansmann, ML Ruland, J Keller, U Newrzela, SHerling, MJost, PJLeukemia, 2016

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The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcome in CLL

Vasyutina, E Boucas, JM Bloehdorn, J Aszyk, C Crispatzu, G Stiefelhagen, M Breuer, A Mayer, P Lengerke, C Döhner, H Beutner, D Rosenwald, A Stilgenbauer, S Hallek, M Benner, A Herling, MLeukemia, 2015

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CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia

Fedorchenko, O Stiefelhagen, M Peer Zada, AA Barthel, R Mayer, P Eckei, L Breuer, A Crispatzu, G Rosen, N Landwehr, T Lilienthal, N Möllmann, M Montesinos-Rongen, M Heukamp, L Dürig, J Hallek, MFingerle-Rowson, GHerling, MBlood, 2013

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High TCL1 levels are a marker of B-cell receptor pathway responsiveness and therapy resistance in chronic lymphocytic leukemia

Herling, M Patel, KA Weit, N Lilienthal, N Hallek, M Keating, MJ Jones, DBlood, 2009

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High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia

Herling, M Patel, KA Teitell, MA Konopleva, M Ravandi, F Kobayashi, R Jones, DBlood, 2008

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TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state

Herling, M Patel, KA Khalili, J Schlette, E Kobayashi, R Medeiros, LJ Jones, DLeukemia, 2006

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A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories

Herling, M Khoury, JD Washington, LT Duvic, M Keating, MJ Jones, DBlood, 2004

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TCL1 expression in plasmacytoid dendritic cells (DC2) and the related CD4+CD56+ blastic tumors of skin

Herling, M Teitell, MA Shen, RR Medeiros, LJ Jones, DBlood, 2003

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